منابع مشابه
Implications of heat shock/stress proteins for medicine and disease.
Heat shock/stress proteins (HSPs) are crucial for maintenance of cellular homeostasis during normal cell growth and for survival during and after various cellular stresses. The HSP70 family functions as molecular chaperones and reduces stress-induced denaturation and aggregation of intracellular proteins. In addition to the chaperoning activities, HSP70 has been suggested to exert its protectiv...
متن کاملOxidative Stress in Veterinary Medicine
Oxidative stress can be regarded as an imbalance between prooxidant/free radical production and opposing antioxidant defenses. There is growing evidence that oxidative stress (OS) significantly impairs organic function and plays amajor role in the aetiology and pathogenesis of several metabolic diseases in veterinary medicine. In many of these cases, it is unclear if oxidants trigger the diseas...
متن کاملStress proteins in biology and medicine: evolution, adaptation and clinical evaluation
I. Stress response: Stress response is a universal phenomenon. The term, “stress”, generally refers to any physical or psychological change that disrupts the organism's balance or homeostasis. Stress activates many systems in the body, however, through a defined mechanism, which starts at the cellular level. All organisms, from bacteria to humans, have evolved mechanisms to deal with significan...
متن کاملCell Stress Proteins in Atherothrombosis
Cell stress proteins (CSPS) are a large and heterogeneous family of proteins, sharing two main characteristics: their levels and/or location are modified under stress and most of them can exert a chaperon function inside the cells. Nonetheless, they are also involved in the modulation of several mechanisms, both at the intracellular and the extracellular compartments. There are more than 100 pr...
متن کاملStress proteins in reproductive toxicology.
Although a wide range of physical and chemical agents disrupt gametogenesis and embryogenesis in animals and humans, much less is known about the mechanisms leading up to these disruptions and the factors that determine whether a particular animal or human will be sensitive to a potential toxicant. Recent research has identified a number of different stress protein families, also known as heat ...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1996
ISSN: 0003-4967
DOI: 10.1136/ard.55.5.287